Retatrutide 5mg 10mg igiciro gito
Izina ryibicuruzwa: Retatrutide
Ibisobanuro: 5mg * 10vial / kit 10mg * 10vial / kit
MOQ: 1kit
Igiciro: 5mg USD320 / kit 10mg USD600 / kit
Aho bakomoka: Ubushinwa
Retatrutide
Retatrutide (LY-3437943) irimo gutezwa imbere mu kuvura indwara ya diyabete yo mu bwoko bwa 2, kubuza gusinzira apnea, osteoarthritis, umubyibuho ukabije n'indwara y'umwijima idafite inzoga.Umukandida wibiyobyabwenge atangwa binyuze munzira zidasanzwe.Umukandida wibiyobyabwenge akora yibasira glucagon imeze nka peptide 1 (GLP-1), glucose iterwa na insulineotropique polypeptide (GIP), hamwe na reseptor ya glucagon.Nibintu bishya bya molekile.
Retatrutide ikora mu kuvura umubyibuho ukabije yibasira imisemburo itatu itandukanye igenga imisemburo: - GIP (gastric inhibitory peptide cyangwa glucose iterwa na insulinotropic polypeptide) ni imisemburo ya incretine isohoka mu mara nyuma yo kurya.Retatrutide itera beta-selile muri pancreas gusohora insuline. Umuti ni peptide hamwe na aside amine ikurikirana.Nibintu bitatu byakira imisemburo ya agonist ya GLP-1, GIP, na GCGR.Byerekanwe kugera ku barenga 24% bivuze kugabanya ibiro kubantu bafite umubyibuho ukabije utarwaye diyabete cyangwa abantu bakuru bafite ibiro byinshi.
Retatrutide isa na Ozempic, Wegovy, na Mounjaro kubera ko ari inshuro imwe buri cyumweru gutera imisemburo ihindura uburyo turya, biganisha ku byiyumvo byuzuye byuzuye no kurya.
Ariko bitandukanye na Ozempic na Wegovy, bigana imisemburo imwe gusa igenga inzara (GLP-1), cyangwa Mounjaro, yigana imisemburo ibiri (GLP-1 na GIP),retatrutideni molekile imwe yigana imisemburo itatu itandukanye igenga inzara: GLP-1, GIP, na glucagon.Icyo gikorwa cya "triple G", nkuko abahanga bamwe babivuze muri iyo nama, bisa nkaho bigira ingaruka zikomeye ku irari ry'umuntu no kunyurwa n'ibiryo.
Mu igeragezwa ryasohotse muri NEJM, abarwayi bafite umubyibuho ukabije bahawe urugero rwinshi rwa buri cyumweru rwaretatrutide(12 mg) yatakaje impuzandengo y'ibiro 58 mu mezi 11.Ibiro byabo byari bikigabanuka nubwo urubanza rwarangiye, byerekana ko ibigeragezo birebire, binini bitararangira bishobora gutanga ibisubizo bitangaje byo kugabanya ibiro.Buri murwayi uri ku kigero kinini cya retatrutide yatakaje byibuze 5% byuburemere bwumubiri, naho kimwe cya kane cyabitabiriye yatakaje 30% cyangwa arenga ibiro byabo.
Mu bushakashatsi busa na retatrutide ku barwayi barwaye diyabete yo mu bwoko bwa 2 bwasohotse muri The Lancet, abarwayi batakaje hafi 17% by’umubiri wabo mu mezi icyenda, ibyo bikaba ari ibintu bitangaje, kubera ko ubusanzwe bigoye ko abarwayi bafite T2D gutakaza ibiro bingana nk'abandi bantu bafite umubyibuho ukabije n'umubyibuho ukabije.
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