SR9009 ibinini 100 ibinini / icupa

Izina RY'IGICURUZWA:SR9009

Umwanya: 10 mg / ibinini ibinini 100 / icupa

Igiciro: $ 80 / icupa

MOQ: icupa 1

Laboratoire: LianFu Bio

Kwandika

SR9009, REV-ERBagonist, byongera guhashya ingirabuzimafatizo zigengwa na REV-ERBα / ERBβ (IC50: 670/800 nM).Binyuze mu gukora REV-ERB, SR9009 irashobora kugabanya ibikorwa bya lokomoteri ya sikadiyani mugihe cyumwijima kandi igahindura uburyo bwo kwerekana imiterere ya genes yibanze muri hypothalami yimbeba.Uburyo bwa circadian bwo kwerekana genes nyinshi za metabolike mu mwijima, imitsi ya skeletale, hamwe na tipusi ya adipose nazo zahinduwe mu mbeba zagaragaye kuri SR9009, bituma ingufu zikoreshwa.

SR9009 (100 mg / kg, ip, ipiganwa, muminsi 30) birashobokakugabanya ibinurekandi ku buryo bugaragarakunoza dyslipidemiyanahyperglycemia.