Ifu mbisi yubuvuzi MK-677

MK-677

MK-677, izwi kandi ku izina rya Ibutamoren, ni umunwa wa SARM utari steroidal (moderi ya selire androgene reseptor modulator) ikoreshwa cyane mu rwego rwo kongera imisemburo ikura mu mubiri.Ibikoresho bikora muri MK-677 ni uruganda rukora imiti ruzwi nka Ibutamoren Mesylate.

Ibutamoren Mesylate ikora mugukora reseptor ya ghrelin, ishinzwe guteza imbere imisemburo ikura.Ni agoniste ihitamo cyane, bivuze ko yibasiye cyane kandi igakora reseptor ya ghrelin, bigatuma imisemburo ikura yiyongera.

Ubushakashatsi bwerekanye ko MK-677 ishobora kongera imisemburo ikura inshuro nyinshi, biganisha ku mitsi myinshi, kugabanya amavuta yumubiri, kunoza amagufwa, no gusinzira neza.Biravugwa kandi ko bifite imiti irwanya gusaza, kuko imisemburo ikura ya hormone ikura ifitanye isano no kugabanuka kwubusaza no kuramba.

Ongera urwego rwa hormone yo gukura.Imisemburo yo mu kanwa itari peptide itera irekurwa rya GH ikoresheje reseptor yo muri glande ya pitoito na hypothalamus, itandukanye na hormone yo gukura irekura imisemburo ya hormone.MK-677 ni imisemburo ikura yo mu kanwa ikura imisemburo, yigana ingaruka za GH mukubyutsa imisemburo ya endogenous.Byagaragaye ko byongera irekurwa kandi bigatanga imikurire ikomeza ya hormone ya plasma, harimo imisemburo ikura na IGF-1, ariko ntabwo bigira ingaruka kurwego rwa Cortisol.

Kimwe n'ibiyobyabwenge cyangwa inyongeramusaruro iyo ari yo yose, ni ngombwa kugisha inama inzobere mu by'ubuzima zibishoboye mbere yo gukoresha MK-677.

Mu gusoza, MK-677 ninyongera yingirakamaro yo kongera imisemburo ikura no guteza imbere ubuzima bwiza nubuzima bwiza.Nyamara, hakenewe ubushakashatsi bwinshi kugirango hamenyekane umutekano wigihe kirekire ningirakamaro, no kumva neza ingaruka zabyo kumubiri wumuntu.Nkibisanzwe, ni ngombwa gukomeza kwitonda mugihe ukoresheje inyongera iyo ari yo yose no kugisha inama inzobere mu buzima mbere yo gutangira gahunda nshya.